Melanin cell is main the function is to form melanin, of human body normal the result that the color of skin with health is melanin synthesis and metabolization balance. When obstacle of melanin cell function or structure are destroyed, melanin is formed decrease or stop, but melanin degradation and destroy still undertake, pigment of its result skin becomes weak or take off break, can cause wind of white purplish or white patches on the skin. The cheese ammonia acid inside black element cell also is a kind of phenolic apperception closes matter, its hydroxyl counterpoint has alkyl catenary of one hydroxide acerbity side, in cheese ammonia acid enzymatic oxidation falls, form the one part of intermediate child, by reductive into half Kun dissociate base, have cellular noxiousness effect, can make fat kind reach lipoprotein kind wait for the cell that make implement film of velar until cell suffers loss, for example cell implement the film of dissolve enzymatic body, be formed the effect that these intermediate product produce in the process by black element, can destroy, the assimilation inside dissolve enzymatic body is enzymatic release cellular oar inside, injure other cell further implement, whole even cell. These intermediate metabolization child are melanin forms the measure that must pass in the process, without these intermediate child cannot form melanin.
Half Kun kind material has double photograph effect possibly to melanin cell, the experiment makes clear, in aether of odd benzene of Kun of skin inunction hydrogen, can make melanin cell and the melanin amount that its make increase on one hand. This may be in half Kun kind below corporeal impact, stimulate the formation of prostate element, and the synthesis that latter can offer melanin, if this causes half Kun kind the Tu Liang outside waiting for noxiousness material is too big, the time that use drug is too long, black element cell can be destroyed, this is double photograph action on the other hand. Or because contact Kun kind corporeal airframe, the biochemical process of material of noxiousness of cleared oneself cell is occurring again congenital blemish, the noxiousness action of these noxiousness material inside body soars, black element cell is destroyed, this is a kind of view of doctrine of self-destruction of black element cell.
Possibly in process of melanin cell self-destruction immune reaction is participated in, the melanin cell that destroyed namely becomes antigen again, form through immune mechanism fight melanin cell antibody, the injury that nigrify pigment cell is reacted by immunity, occurrence vicious circle, melanin cell damage is more and more, more and more serious.